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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41305d7ccc453a2da4b59cdd2f7f789bb30ba1611180b0e9fd6b3bc1ff9b21cb' 
  AND token = 'wVX1JqLVI+gU+AznevSd56LJQTytsCOvUzdTzDeQrSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}