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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea38b53b61499bf51e42dbfbf94fa358c0da2d02b49fb5b6e1479bffb39ed3bc' 
  AND token = 'Ga7xqMbW35C1ohL3O9fcahPZJRZDs7qvWT3js7Irq9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}