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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888f052243dcf72fbabe01f9b6cbefd3ccc3a96325ea14616aaab5cd3b3b52d1' 
  AND token = '4xiCbgL4+6HxHG3rtBbR/w2YFLXWvfrXrGwstV5/Cgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}