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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2268f8222d6a73319bae341539939521a178a0a3ebeddc2e7f720480ce6faf20' 
  AND token = 'VXjQL065R0NNTb3HGlgBOzUeH9006aWNyyQvQ70ehlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}