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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae109ec360aa6f4bb0e8b226f6142828ba37165169ca49524b96bd25c12f0bf' 
  AND token = 'HxZdqpAR/zAB+vHllaOfvt0vuiYaHP3RvZZ403y2JOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}