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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09500f1ff8b666950cb0f9f273e501649402abb945e5786702939df27f0eb5a7' 
  AND token = 'KujIpAe/ctFAHEtu1zV2FPEew77HoH2eRq0McUrrDsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}