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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d6cd15afcb8c0503196296fb5401d09d7446639a012f5e97c9aeb49fdf8b61e' 
  AND token = 'kMPm5tMIwTyM2X3V+E2vRs7hZooW+q1gXvlDVJ8Xg0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}