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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a720511d301b2451ce97d1f8f314bb0e2180a8a3c0c98843822b9d7da8b75ef' 
  AND token = 'XQ8cxrJQIXAbXoFgNq+bQANl2CS72J6aY2TUkQZ3pU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}