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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '867dec7356045f39453032fe308c3170651f24ac4cce04f5b8c544a24ccf27c4' 
  AND token = 'zRQE4nV8bIlShow+Rr/2q0RBJI+Xqe+o7UVtqgbPnZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}