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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec2d0c0b00c135e687c320510eee5161dcf844a151bc0dbe1c0886dd64c90da6' 
  AND token = 'bBOrYv3bBF5qlIK6DO5tpJ0+fb1NKtkF8DN/HY9vXm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}