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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4ce1f70ae6be48516290eae1b30c96641f7155fd2b410674729b6892e8c235' 
  AND token = 'SlsXo2IlWI38nA/CAInRvYR5kZR1TOBTqFyABxQDOG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}