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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60ca7521336297a553bf4c5b85aa30b53f41302609a3ba588720badaab674e77' 
  AND token = 'l7QrjarLVNvehfMBFme+oJOFmoZl2zPV6N4QtkzWjPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}