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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca0d49ab9f01607e1d3ba96629368a2788daae6f25e5f589db7d3fbbda2887ac' 
  AND token = 'EjglVniHOmV8XVVqJ5DQSOt2AMQhwiQtI9hnO41qsl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}