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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5ab0214ae6f9941d66e25b3f73a5f59e46867640eeb51229ab006ddbb50f025' 
  AND token = 'XKIR1nM6oe2o90GBfQA8kVa8UTWFzFhra1XgyVsU72c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}