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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdea9bfbaa866443d21b12608e7d6ac4868a600224e1f51e8456cd600b58d80f' 
  AND token = '2j3bDSt14l/dq9Z5DIGawNZCyqvbIE5ZRmkSUizVyD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}