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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6ca14c2b7cb5395f7c852c1d1062577aa8c90f952c6d268912ef65b083b6d1c' 
  AND token = '4f78NrQeS2mZbZxnrhffthsqPHOKGZphUmlyAp/vV5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}