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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7275fe83311a1b024658942ca0c4cc443a224f6f4ce3263b2ba991794be6251b' 
  AND token = 'yggANKa6sPpbR+KItas3DvkjU/e7aImgvSvUK0ZLfpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}