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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9820f37a5c4e7934cf3cf0675d9344b30654a65da620021feb389c6327c289' 
  AND token = '8XSwFQiBBckzi3niNL/nPOqRS8tkG6031ljiFlXRpfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}