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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e2079d32ca2f611c6e73ae1fda30c35deec4f11ae8d1cd44d3d825ac5b653af' 
  AND token = 'XClyptVbViAtOLg4AbTdGSyx8e2+hhRW/f8nPjGMzew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}