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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '794ddd244e56139fa5011b6d77f99bcd6652c0c125b3045225149ff92d2861e7' 
  AND token = 'HfH36xW/DWS7Y1Jt0TTl6KMgMcimnOuhQOsP+q0bCII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}