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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e851c7e4fa6e7f87462f8c9e7f17f346a42ecb90a0f64085b5e03eaf537488d' 
  AND token = 'UcgLsSzRC9rBUcNBgH1IM02dgmcEGrqU8SLAA5zHJyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}