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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '018fe1ba3cdacdba862eab6bbaa6581e2dc0a2bf7433541351bdbe1c3a189648' 
  AND token = 'z+WwmwLDI6X7yMS1cwP6d4gBjbybD2hK5T9aUccbfIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}