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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb126b531f3e66ad8bed317e9d377840a421fa903545a826860c75b71994b0c' 
  AND token = '4NarwhgyrybnTs5eACuwiMg68vgP1zvFotVRNZJEOBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}