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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8564a25575997994aa3602d91f24ae2a9eef48b6e62561ea71faa499e293e392' 
  AND token = 'mKhSYkEuvWmcgVmDUr/kN3xZ0sp+Js35uMetqXrHVlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}