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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05e56b66d93bb359610870d1a81d008d02f6b893368b2013636801a77c7e87f' 
  AND token = 'Wy0hZBcUjBy9xwLE8MbBl8ow0+YV7CJpLKAnQKdEigI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}