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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de9950cf1928a7a6f2e85a5831ea9fa0a0378addf25e9c73911d21cf38a3feb' 
  AND token = 'CicKBiwjvswJd1xq2CA7Hi5+0cVK2/ckckRLWsAL+54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}