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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101601a49f1be29da9f4644b021b24edff094f9079263d5f244b0ecd48b8ced2' 
  AND token = 'ioOImSg//TG80+RQc356QCYjg5msoTN9YOkRoUe8fGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}