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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4349f570bd6d60d99e56bdbcc9a3e1473966ae35e84dd45f719f0c3c6d51d3d8' 
  AND token = 'pFwv24QFYdViGEBZoSHv1A0RkUrHygFghY7MvLN5YbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}