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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73bd6809171159ec79eeb4f9876db504c9b05c3d4dad16a41d0c9a28824e91e2' 
  AND token = 'dz+hDg90+Lt2nqoJRQs81s8Yn8sYmSB8i1jdTvLV7Yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}