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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec22d0f87318f5bb81b29469ca1c7358c3aea9f2c65cc84e8f738f0b26dd7b1a' 
  AND token = 'ydxKMQOnNNsJW6F0Y/zNHKmmhN6QKI4TCrgEAxXqHHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}