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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45399a4debfb50199c2c99a02684b5f489c2c1eb3bb01a34b40b1dc67af85273' 
  AND token = 'vV1g2Em9K4mObITtgP82rOdoX+SrGsfjFFFdqi+nyVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}