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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '995e72202c98bb290f2148a14916abfe7a243b6baf2ca975a05bcb9ad1fcc53f' 
  AND token = '2c2bmHWUIOSdjseFSS8wfa7Rp3PoyUq7qdq5c73UuB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}