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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1557fbf2ebd4bfc766edaa73339266eb270793ccf4a57e5f0b1398893914b859' 
  AND token = 'Ore3mbszeuRketV28xKzjZrryIQAsAPoTvAgnB1Isug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}