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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ff59922d5ab5eebe87fb465fab555e330461061c36f873b4dba9c9275e0b50' 
  AND token = 'EdDRlR2khmLQ4D1dvrQTNc1sQUl4vkjp1BkKGvEqaEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}