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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08222a957ec18e47b9aaa4f076a5d27500176dc1c0f2237c6fff265f7e66c641' 
  AND token = 'oOTfQrK35Jx/Zf4t5ILwNP9JQOV0I05Fv8MDCaDRnWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}