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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c09b525a2cbf359857bce43ba15b521c7dfe677c09c380f7b0a4dd0503a1b8' 
  AND token = 'dKIsCvGNpPaHon0o1HCV6LCpQ78+SAB+1Jk6ky4U8H4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}