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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47ecff565f3c781d3e6771e865f89b1fd77b7214cf77d01bf8127785a25236d1' 
  AND token = '66pRKdLHW5Nf0rU/Vr3Gyrh3TFZBhAmKxYSLaB2wsok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}