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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a532d090295a2a5134bbbe5b178b4169b9c1b23f7b8e8fd345c27616075b14a1' 
  AND token = 'VYEaptjQILxTNjr8RpStV1+/YdaTqS6LSJo3nkdoDIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}