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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4748dd901cf7efbb1e8b9af393930d893cb30442e3ffaf9207431fd89790ad71' 
  AND token = 'kAxmWfWB8AFa6z7aFfSivnoPVgM3zbOR+hJOTJuA7zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}