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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c104e5727d7a7886e8e0b5d0cb6c29d7053392a35357ca577c0d1d6df267e4d7' 
  AND token = 'PrT3GFmUHCAxl26U9cs4tPIXnKcTjLj32WX4G4E/mEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}