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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2dd0bbedad7163bdb5c8b5381b0c081a1288559bb36c9705f0beb1995a37e41' 
  AND token = '69N1kIb1WToM2lktrXBrSoXbpTfE5T4hGkZsudwpV00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}