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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b300d1a51db248e229ee705b4c176abc9b1d926962c012826ee81b0f040a0c' 
  AND token = 'ClJChj5g5FMA1B88ARYGy4A2nWKWGNSriwYPxBc7Bo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}