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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e228d1c183dc9e669d34810e6e9c420f1e42aafa14b29c57f3ea1a06d4c2e83' 
  AND token = 'WV0NFWRXMIjwMVUxlHYT+CUa94lq+VcNGCgiv7XPQ4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}