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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3588c59cccc8f2ab9df045eb678d5fc9bb6c408659d399e356fc885c9b414551' 
  AND token = 'ygJa1JMcidV3Zbbf3wJ9Q84DH6o6KNAoPDHFwkEfdqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}