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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4724fc5b465ea6d2b1b3a72296fdef37213c9b3cd4702ba62971384daca6f6f0' 
  AND token = 'dzG44lDCUj/BDSvc6Cqo4eN3FsX74nAUAhGgf8+rAQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}