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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b49f74461324db3db1abcab656af238c9247a83615b98999b034d6f808cf9a' 
  AND token = 'u2M0u0n78TfNFsb9jzVFqTSYA/5koUwbrtr0/FmGx7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}