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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cda24ebab820e3cd753008c9bd2a1255fd1092e6a0fdcb766af0fb2b1fa1b89' 
  AND token = '+1jLPnTGiQT9yjuLceS6vzbyqt7h5bg7TLBfycGk5yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}