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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cec418e3b0f9ec93f6f881d892e0a4c900bde8eb6096245a4d79f50d9ad995a' 
  AND token = 'X8jpFw5LezFkAzsrrgjT1WW2fLSxbNNG6UtAQ5JefU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}