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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59761182631edcf3bd1d2369316c684947717b4b6feca5205ee58817a4b8e522' 
  AND token = '3V728Nf7MKpGe63TMoE3TzMzGvydaA401Ozf/R96nLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}