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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e76e4ea274bb5326db83513da45bc01f5768a42f2e4ff69f9e919571ccef28' 
  AND token = 'mm0iK8h6oyf2e+L7r7MA5Fe8ZaRDfZi2JnqY+rxZEnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}